Soho Flordis International

Essential fatty acids (EPA, DHA & GLA)

Essential fatty acids

Omega-3 and omega-6 fatty acids support concentration, learning, reading and healthy brain development1-4

The role of essential fatty acids (EFAs), which include omega-3s (EPA and DHA) and omega-6 (GLA), to support healthy brain function and learning development continues to grow as an area of research. 

 

EQUAZEN eye qTM is made with a scientifically developed ratio of EPA:DHA:GLA (9:3:1), which has been shown in multiple clinical trials to support concentration, learning and reading.

 

Discover more about the clinically researched combination used in EQUAZEN eye qTM and the key studies that support its benefits.

Essential Fatty Acids in history

Dietary fats are part of our everyday diet. They belong to a larger group of compounds called lipids. Lipids help build our cell membranes and are vital to our central nervous system – making up about 50-60% of the weight of our brain.5

 

Of these brain lipids, approximately 35% are made up of polyunsaturated fatty acids (PUFAs), which include the omega-3 essential fatty acids, EPA and DHA and omega-6 essential fatty acid, GLA. 5  

 

These essential fatty acids (EFAs) are PUFAs that may not be made or stored by your body and it is therefore recommended to be provided through our diet.6  Over the years, fish oil has been recognised as a rich and important source of omega-3s (EPA and DHA) while evening primrose oil contains a natural source of omega-6 (GLA).

 

These EFAs are known to play important biological roles, being structural and functional components of cell membranes and research suggests they have a profound influence in the development of the central nervous system, brain and neuronal function. 6

Essential Fatty Acids in history

The optimal combination used in EQUAZEN eye qTM

EQUAZEN eye qTM was developed based on years of research and expertise to provide an optimal balance of fish oil rich in omega-3s (EPA & DHA) and evening primrose oil rich in omega-6 (GLA). This combination is referred to as the Equabalance ratio EPA:DHA:GLA that is 9:3:1.

This optimal balance of EPA : DHA : GLA has been researched in 12 clinical studies.1-4, 7-14  

Evidence shows EQUAZEN eye qTM can help support:1-2

  • Concentration/attention 
  • Learning 
  • Reading 
  • Language development
  • Working memory 

Always read the label. Use only as directed. If symptoms persist consult your healthcare professional. Use in children under 3 is not recommended.

 

The optimal combination used in EQUAZEN eye q<sup>TM</sup>

Research on how essential fatty acids work

The essential fatty acids EPA, DHA and GLA have long been recognised for their role in the structure and function of cell membranes, anti-inflammatory processes in the body and growing research shows they can play an important role in supporting healthy brain function and development. 6

The pre-clinical for essential fatty acids suggests they can help support:

 

  • Cell membrane structure, function and communication (including neuron cells)15-16
  • Nervous system function and development 15-16
  • Anti-inflammatory effects 15-16
  • Processes the can  play a role in healthy neuronal function  17-18
Research on how essential fatty acids work

Clinical studies on EQUAZEN

EQUAZEN eye qTM has been researched in multiple clinical studies involving both mainly children and also adults.  The evidence demonstrates the beneficial effects of the Equabalance ratio of EPA:DHA:GLA = 9:3:1  used in the EQUAZEN eye qTM range, with significant improvement in concentration and learning development.

Stough 2001

154 children over 3 months

Significant improvement

vs. placebo for performed tasks reflecting:

  • Concentration and attention Learning and language development including reading and visual analysis Working memory

Johnson et al. Child Psychol Psychiatry. 2017 Jan;58(1):83-93.

Parletta et al. 2013

409 children over 40 weeks

Significant improvement

vs. placebo for performed tasks reflecting:

  • cognitive and learning development concentration and attention working memory

Parletta et al. Prostaglandins Leukot Essent Fatty Acids. 2013 Aug;89(2-3):71-9.

Sinn et al. 2008

167 children over  30 weeks

Significant improvement

vs. placebo for performed tasks reflecting:

  • concentration and attention learning and language development

Sinn, N. et al. Prostaglandins Leukot Essent Fatty Acids. 2008 Apr-May;78(4-5):311-2 sin 6.

Johnson et al. 2009

75 children & adolescents over 6 months

SIGNIFICANT IMPROVEMENT

  • concentration and attention

Barragan-Perez, E.J., Heredia-Barragan, I., and Huerta-Albarran, R. 2011. 17(4): 148-153.

Richardson et al. 2005

117 children over 6 months

SIGNIFICANT IMPROVEMENT

vs. placebo for measures reflecting:

  • concentration and attention learning such as reading and spelling

Richardson, A.J. and Montgomery, Pediatrics. 2005 May;115(5):1360-6.

Flordis Difference

EQUAZEN eye qTM with Equabalance ratio 9:3:1

 

There are now hundreds of formulations containing omega-3s or omega-6 as the main ingredients. So what makes EQUAZEN eye qTM with the specific ratio EPA:DHA:GLA = 9:3:1 different?

 

  • High quality with the optimal balance of EPA, DHA and GLA  
  • Consistently reliable, batch after batch
  • Researched in clinical trials

That means, you can be confident that the EQUAZEN eye qTM product you are getting contains the same balance of ingredients that has been demonstrated in clinical research to support concentration, learning and reading. That’s the Flordis difference.

EQUAZEN eye qTM: EPA:DHA:GLA = 9:3:1: A Summary

Consistent quality

Through our rigorous processes, quality controls and extensive testing we help ensure that our clinically researched ratio 9:3:1 can provide the health outcomes demonstrated by clinical research

Clinically researched ratio of fatty acids (EPA:DHA:GLA=9:3:1)

Formulated to provide an optimal balance omega-3 and omega-6 essential fatty acids

12 Clinical trials

EQUAZEN eye qTM clinical studies support its role in improving cognitive functions in healthy subjects6-11

Recommended and used worldwide

to support healthy brain development

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References

1. Johnson et al. Child Psychol Psychiatry. 2017 Jan;58(1):83-93.

2. Parletta et al. Prostaglandins Leukot Essent Fatty Acids. 2013 Aug;89(2-3):71-9.

3. Bauer I. et al. Hum Psychopharmacol. 2014 Mar;29(2):133-44.

4. Bauer I. et al. PLoS One. 2011;6(12):e28214.

5. Assisi A. et al. Fish oil and mental health: the role of n-3 long chain polyunsaturated fatty acids in cognitive development and neurological disorders. International clinical pharmacology 2006,21:319-336

6. EFSA Journal 2010;8(10):1796. DOI:10.2903/j.efsa.2010.1796

7. Sinn, N. and Bryan, J Dev Behav Pediatr. 2007 Apr;28(2):82-91.

8. Barragan-Perez, E.J., Heredia-Barragan, I., and Huerta-Albarran, R. 2011. 17(4): 148-153.

9. Johnson, M. et al. J Atten Disord. 2009 Mar;12(5):394-401.

10. Johnson, M. et al. J Atten Disord. 2012 Dec;4(4):199-204.

11. Sinn, N. et al. Prostaglandins Leukot Essent Fatty Acids. 2008 Apr-May;78(4-5):311-2 sin 6.

12. Barragán E, Breuer D, Döpfner M. J Atten Disord i-9. 2014.

13. Richardson, A.J. and Montgomery, Pediatrics. 2005 May;115(5):1360-6.

14. Milte et al. Nutrition. 2012 Jun;28(6):670-7.

15. Wiktorowska-Owczarek A, BereziƄska M, Nowak JZ. PUFAs: Structures, Metabolism and Functions. Adv Clin Exp Med. 2015 Nov-Dec;24(6):931-41. doi: 10.17219/acem/31243.

16. Sergeant S, Rahbar E, Chilton FH. Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes. Eur J Pharmacol. 2016 Aug 15;785:77-86. doi: 10.1016/j.ejphar.2016.04.020.

17. Bell JG, MacKinlay EE, Dick JR, MacDonald DJ, Boyle RM, Glen AC. Essential fatty acids and phospholipase A2 in autistic spectrum disorders. Prostaglandins Leukot Essent Fatty Acids. 2004 Oct;71(4):201-4.

18. Bennett CN, Horrobin DF. Gene targets related to phospholipid and fatty acid metabolism in schizophrenia and other psychiatric disorders: an update. Prostaglandins Leukot Essent Fatty Acids. 2000 Jul-Aug;63(1-2):47-59.

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