SFI Health


For relief of premenstrual symptoms and MCI's (Menstrual Cycle Irregularities)


For a time each month, before your menses, are you feeling not quite yourself? Perhaps your mood changes and you feel more worried and irritable? Or are your symptoms more physical, such as headaches, or feeling uncomfortable due to cramping, bloating and breast soreness? If so, Premular may be right for you.


Premular is a natural medicine that’s clinically proven to relieve symptoms of premenstrual syndrome (PMS).1-3 Premular not only relieve symptoms, but can help improve menstrual cycle irregularities associated with PMS.


Always read the label. Use only as directed. If symptoms persist, see your healthcare professional.

Premular has been shown to:

Provide multiple symptom relief

Provide multiple symptom relief

Including breast soreness, mood alterations, irritability, headaches and bloating.1-3

Provide sustained symptom relief

Provide sustained symptom relief

Sustained relief of PMS symptoms shown over time2

Help have  a regular period

Help have a regular period

Helps relieve  menstrual cycle irregularities4

Research & Evidence

Premular: Key Ingredient

Premular contains an exclusive extract from the plant, Vitex agnus-castus, also known as Chaste tree. The specific extract used in Premular – known as Ze 440 – has been researched in multiple clinical studies to  relieve PMS symptoms and menstrual irregularities.1-4

Learn more about Vitex agnus-castus
trials & studies
Majority of women reported >50% improvement in PMS symptoms1

Did you know that 70-90% of women may experience at least one symptom of PMS? 5,6
Find out more about how Premular can help relieve premenstrual symptoms.

Our Source to Patient Philosophy

What do our products have in common?

The products in our range have a shared story: they are handled with exceptional precision and care and backed by rigorous science.

Learn about the six precise steps we take

Using Premular

Recommended dosage & directions

Recommended dosage and directions
Adults and adolescents: take 1 tablet in the morning, preferably with food.


For best results take Premular for a minimum of 3 months, or as recommended by your healthcare professional.


Your health practitioner can help you decide whether Premular is right for you. It is always best to discuss all of your symptoms with your healthcare professional to determine whether Premular is a suitable option for you and how to use it.


Premular is well tolerated based on clinical research and years of worldwide use.


There are no known reported interactions between Premular and other medicines. However, if you are taking the oral contraceptive pill or other prescription medication, it is important that you talk to you healthcare professional before taking Premular.


Distributed by Soho Flordis International South Africa (Pty) Ltd.  |  Company Registration no.  004/035255/07.
This unregistered medicine has not been evaluated by the SAHPRA for its quality, safety or intended use.

Active ingredient
Chaste tree (Vitex agnus-castus)

Each tablet contains Ze 440 extract equivalent to dry:
Vitex agnus-castus fruit 180 mg


Premular is a natural medicine that has been proven to relieve the symptoms of PMS in clinical research.1-4 It contains a particular extract from the fruit of Vitex agnus-castus, called Ze 440. This specific extract Ze 440 and optimal dose has been tested in placebo-controlled clinical trials, so you can be sure that Premular has demonstrated relief of PMS symptoms.


Natural medicines can vary considerably depending on the species of plant chosen, the way it’s grown and harvested, and the extraction and production process. So it’s essential to ensure the product you receive is the same as that shown in clinical studies to relieve PMS symptoms.

There are no known reported interactions between Premular and other medications.  However, if you are taking the oral contraceptive pill or other prescription medication, it is important that you talk to you healthcare professional before taking Premular.

The minimum recommended period is 3 months. However, depending on the condition and symptoms, Premular may be continued long term under the recommendation and guidance of your healthcare professional.

Premular is available from pharmacies, selected health food stores and natural health practitioners. Click on Find a Store to find a list of practitioners and pharmacies in your area that either stock Premular or will know how to order Premular. Even if your local pharmacy is not on the list, they will be able to order it in for you. 

Premular is not indicated for use during pregnancy or while breastfeeding. Although there are no reported safety concerns, there are no published studies to establish safety for the use of Premular during pregnancy or while breastfeeding. It is important to speak with a healthcare professional if you have specific questions or concerns. 

It is important to discuss this with your healthcare professional, including the anaesthetist and surgeon.

Yes. Premular contains a very small amount of lactose (40 mg) in each tablet.

Premular has no known adverse effects on the ability to drive and operate machinery.  

Premular is indicated for use in adults and adolescents with PMS symptoms. It is not recommended for use in children under 12 years.


1. Schellenberg R, et al. BMJ 2001;322:134-137.

2. Berger D, et al. Arch Gynecol Obstet 2000;264:150-153.

3. Schellenberg R, et al. Phytomedicine 2012; pii: S0944-7113(12)00280-2.

4. Eltbogen R, et al. J Gynäkol Endokrinol 2015; 25(2):10-15.

5. Tschudin S, et al. Arch Womens Ment Health 2010;13(6):485-494.

6. Joshi JV, et al. J Midlife Health 2010;1(1):30-34.


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What is PMS?

What is PMS?

Lifestyle insight

The complex of combination of physiological, physical and psychological changes that occur monthly, during the luteal or second phase of the menstrual cycle, constitute the premenstrual syndrome (PMS).

PMS Symptoms

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